Prognostic value of E-cadherin expression in 413 gastric carcinomas
نویسندگان
چکیده
منابع مشابه
Expression of E- and P-cadherin in gastric carcinomas.
The expression pattern of two Ca2(+)-dependent intercellular adhesion molecules, E- and P-cadherin, in 54 surgically resected gastric adenocarcinomas was examined immunohistochemically. E-cadherin was expressed uniformly at the cell-cell borders of most of the differentiated and adherent-type undifferentiated gastric adenocarcinomas, showing that E-cadherin serves as the main cadherin molecule ...
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PURPOSE To analyse the negative versus positive immunoexpression of E-cadherin in patients with primary ovarian carcinomas, and determine its significance in relation to clinicopathological features, overall and recurrence-free survival (RFS). PATIENTS AND METHODS The protein expression of E-cadherin was immunohistochemically evaluated in formalin-fixed, paraffin-embedded samples in 104 patie...
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BACKGROUND E (epithelial)-cadherin, the cell adhesion molecule also considered a potential invasion/metastasis suppressor, is mutationally inactivated in nearly half of all undifferentiated-scattered (diffuse-type) gastric carcinomas. In addition, silencing of E-cadherin by CpG methylation within its promoter region has been reported in several gastric carcinoma cell lines. We investigated the ...
متن کاملExpression of E-cadherin in oesophageal carcinomas from the UK and China: disparities in prognostic significance.
AIMS To study the expression and prognostic significance of the cell adhesion molecule E-cadherin in oesophageal tumours from the UK (low risk area) and China (high risk area). METHODS E-cadherin expression was measured immunohistochemically in resected tumours from 17 patients in the UK with adenocarcinoma, 23 patients from the UK with squamous carcinoma, and 30 patients from China with squa...
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Introduction: Gastric cancer is a major public health issue worldwide. The factors that initiate cancer are not well understood, however aberrant expression of genes is associated with this cancer. TRIP13 plays pivotal roles in meiotic recombination, DNA repair, and cell cycle progression. An increasing body of evidence suggests that TRIP13 may possess functions other than meiosis and mitosis, ...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1996
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(19960621)69:3<184::aid-ijc6>3.0.co;2-w